Abstract synthetic protein expression element

An older woman is smiling for the camera.

IDENTIFY THE UNIQUE ELEMENT THAT BOOSTS PROTEIN EXPRESSION

From biotechnology tools to therapy discovery: Our protein engineering platform enhances production yield and the quality of your end product.

IDENTIFY THE UNIQUE ELEMENT THAT BOOSTS PROTEIN EXPRESSION

From biotechnology tools to therapy discovery: Our protein engineering platform enhances production yield and the quality of your end product.

Technology

OPTIMIZE YOUR PROTEIN PRODUCTION SYSTEM – FROM mRNA TO SYNTHETIC PROTEINS

Simultaneously analyzes over 5,500 of naturally occurring and synthetic signal peptides

Significant improvements in protein yield (up to 500% in external validations)

Especially powerful for difficult-to-express proteins that hinder development

Compatible with expression optimization of any mammalian protein production system: from mRNA therapies to synthetic proteins

News

PRESS RELEASE

Stay informed: Announcements, key milestones, and what we are working on next.

May 20, 2025

Veli-Pekka Jaakola joins Avenue Biosciences as Chief Technology Officer

October 22, 2024

Avenue Biosciences Raises $2.5M Seed to Scale AI-Enhanced Protein Engineering

October 7, 2024

Avenue Biosciences Welcomes Industry Experts to Advisory Board for Market Insights and Focused Growth

Machine learning transforming biosciences

The Technology

A BLEND OF SYNTHETIC AND ORGANIC BIOLOGY

Our platform is a unique combination of high-throughput chemistry and synthetic biology, powered by machine learning and AI algorithms.

It is the most powerful solution to engineering N-terminal signal peptides: An element significantly underutilized in protein biologics.

Enhance any protein production system: From protein biologics and biosimilars to any mammalian protein-based biotechnology tools.

APPLICATION POSSIBILITIES

ENABLE PRODUCTION OF DIFFICULT-TO-EXPRESS PROTEINS

ENHANCE PROTEIN, mRNA & VIRAL THERAPIES

SINGLE CHAIN PROTEIN EXPRESSION OPTIMIZATION

MULTI-CHAIN PROTEIN EXPRESSION OPTIMIZATION (mABS, ANTIBODIES)

BOOSTING VACCINE & DRUG DISCOVERY

MAMMALIAN CELL LINE DEVELOPMENT

THERE IS A GROWING DEMAND FOR PROTEIN-BASED BIOLOGICS AND USE OF PROTEINS AS TOOLS FOR DIAGNOSTICS.

Benefits

FEWER BOTTLENECKS, MORE BREAKTHROUGHS

Increase the success of therapeutic and biotechnology development with precise, scalable protein engineering

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CHALLENGES INTO VICTORIES

Reduce time-to-market and production costs in pre-clinical therapeutic development

Preclinical development process using latest technology

UNLOCK BREAKTHROUGHS FASTER

Gain a critical advantage and unique IP with novel molecular components

Unique naturally occurring and synthetic elements

OUTPACE THE COMPETITION

Laboratory professional working with precision and experience.

About

WHO WE ARE

Avenue Biosciences is a team of life science and technology visionaries. We resolve fundamental challenges in therapeutic development through powerful protein engineering that combines organic biologics and machine learning. Our proprietary method is based on years of scientific research from the University of Helsinki, Finland.

This novel method has the capacity for analyzing thousands of protein expression elements at once to find a handful of promising candidates. The resulting unique molecular combinations can provide substantial value that is worth millions to therapeutic developers tapping into countless opportunities in protein biologics drug discovery.

Ville Paavilainen

Research Director, University of Helsinki

Ville Paavilainen

Research Director, University of Helsinki

Machine learning and faster discovery in biotechnology.

REVOLUTIONIZING HEALTHCARE THROUGH INNOVATIVE SOLUTIONS

Discover our cutting-edge technology and services that drive advancements in biopharma.